What is DPI Covid-19 screening?
Rapid Laser–based DPI (Diffractive Phase Interferometry) technique for Covid-19, based on optical-phase modulation, can give a signature of infection within a few seconds. It is robust and a novel and efficient optical way to interrogate the morphological change in the blood of mass population in a ultrafast time scale. The process is known as mass screening for the purpose of identifying viral infection in the blood cells.
Why is this so different to the current methods of Covid-19 testing.
The DPI test is rapid, easy to use, mobile and 95% accurate.
The DPI test show the infection before any signs are showing with the patient, this means that the infection can be found before at any time, this includes the current “unknown” time where we currently have to wait to see if we get ill in the 10 days of isolation.
The DPI test can be done daily, it is quick and easy, reducing the lost time of self isolation, removing the waiting period, removing the requirement for intense laboratory time and expense.
The DPI test give the piece of mind and allows lives to begin to move towards a normal life.
This is a screening process, to detect the presence of the infection. Where the device show an abnormal cell deformation, that is not recognised by the AI, a swab test should be the next action.
It should also be noted that there are a range of other factors that can make the red cell deform, to account for this, the device uses a central remote database and AI to allow continuous updates as new results of the effect of different combinations of drugs show a deformation pattern.
Who can operate, skill levels required?
Training is not a technical issue, anybody with first aid experience can be trained very quickly.
Anybody who can be trained to take a finger prick for the blood sample.
Real Time Optical probing of sub-micrometer Deformation in the Blood cells based on Diffractive Phase Interferometry
Blood Sample was extracted using Finger prick. Extracted blood is sandwiched between microscope cover slips and then shine the desirable laser light on it. Blood cells with different dimensions and morphology can generate different effective refractive indices and thus provide different phase distribution as Photons travel along random optical paths. BY judiciously modulating the optical phase-front of a laser beam -with relatively small changes of blood cell morphology can significantly change the angular distribution due interference between the scattered and the refracted light causes the anomalous Airy disk diffraction pattern. The measured light scattering in the small- and wide- angle regimes are thus analyzed using DPI post processing computational algorithms that showcase the optical pattern for the detection of SARS-CoV2 Virus. Thus, rigorously analyzing the angle-dependent scattered speckle characteristics in the pattern, we established a functional correlation between the relevant range of angle through which the light was scattered and the deformed cell structure that would determine if a person is infected or healthy.
This assay significantly detects the impact of SARS-CoV2 Virus on blood cells qualitatively. Both positive and negative controls for the tested effect of viral infection showed expected results. Not detected results may not always rule out current or future infection. Please correlate with clinical findings and repeat if necessary. Lower respiratory samples are recommended in severe and progressive disease. Positive result indicates the Blood sample from SARS-CoV2 was detected and the patient is infected. Negative result indicates SARS-Cov2 Virus not present in specimens above the limit of detection.